Results 251 to 260 of about 2,073,428 (292)

Learning Health Systems, Equity, and Bounded Justice: A Critical Scoping Review. [PDF]

Learn Health Syst
Thambinathan V, Lynch K, Moya M, Flores MG, Musalia RM, Rubin J, Lepczyk J, Williamson FA.   +7 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Cone-beam CT evaluation of orthodontic treatment outcomes for multiple impacted maxillary anterior teeth. [PDF]

BMC Oral Health
Chen L, Mo S.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Assessment of marginal bone loss, distal caries, and external root resorption in second molars adjacent to impacted third molars: a retrospective CBCT and panoramic study. [PDF]

BMC Oral Health
Abat VH, Keser G, Yülek H, Gencoglu N, Namdar Pekiner F.   +4 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Endoscopic management of gallstone large bowel obstruction at a sigmoid diverticular stricture secondary to cholecystoduodenal fistula. [PDF]

J Surg Case Rep
Feng LR, Peter LG, Barrett CD, Matos MA, Henry R.   +4 more
europepmc   +1 more source

Advanced deep learning techniques for classifying dental conditions using panoramic X-ray images. [PDF]

BMC Oral Health
Golkarieh A, Afjehsoleymani B, Kiashemshaki K, Boroujeni SR.   +3 more
europepmc   +1 more source

Correction: Model based noise correction enhances the accuracy of pancreatic CT perfusion blood flow measurements. [PDF]

Sci Rep
Vats N, Mayer P, Kortes F, Klauß M, Grenacher L, Kauczor HU, Stiller W, Skornitzke S.   +7 more
europepmc   +1 more source