Results 271 to 280 of about 2,037,826 (341)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Prevalence and classification of canine impaction in the Saudi Arabia Population of Jeddah and Al-Madina Al-Monawara: A retrospective radiographic study. [PDF]

J Orthod Sci
Alhajrasi MK, Abualnja OA, Altouki NH.
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Effect of ozone therapy on post-operative pain following mandibular third molar surgical extraction: a split-mouth randomized clinical trial. [PDF]

Clin Oral Investig
Guaschino L, Vanzanelli A, Babando P, Ricotti A, Ramieri GA, Roccuzzo A, Appendino P.   +6 more
europepmc   +1 more source

How Have Changes in Human Capital Investment Impacted the Development of the National Economy of Finland

, 2018
Tom Eklöf
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Management of impacted fetal head at caesarean section − Current practice and future development

Laura van der Krogt, Natalie Suff, Lisa Story, Andrew Shennan   +3 more
openalex   +1 more source

Reliability of Pederson Scale in Surgical Extraction of Impacted Lower Third Molars: Proposal of New Scale

, 2014
Mohamed Yaser Kharma, Salah Sakka, Ghassan Aws, Basel Tarakji, Mohammed Zakaria Nassani   +4 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

How should APOBEC3-induced resistance mutations be considered in the management of antiretroviral therapy? [PDF]

J Antimicrob Chemother
Gilbert M, Ferré VM, Guilbaud R, Digumber M, Peytavin G, Damond F, Le Hingrat Q, Yazdanpanah Y, Descamps D, Charpentier C, Joly V, Ghosn J.   +11 more
europepmc   +1 more source