Results 51 to 60 of about 2,037,826 (341)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Visibility of the mandibular canal on cross-sectional CBCT images at impacted mandibular third molar sites

Biotechnology & Biotechnological Equipment, 2016
The aim of the present study was to assess visibility of the mandibular canal (MC) on cross-sectional cone beam CT (CBCT) images at impacted mandibular third molar (IMTM) sites. CBCT images for 150 IMTMs were selected for the study.
Mustafa Alkhader, Fadi Jarab
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Surgical Management of Various Types of Maxillary Canine Impaction: A Narrative Review [PDF]

Reviews in Clinical Medicine, 2019
With the exception of the third molar, maxillary canine impaction is considered to be the most common form of tooth impaction. The position of the permanent maxillary canine at the angle of the mouth is strategically important in preserving the harmony ...
Arezoo Jahanbin, Mostafa Shahabi, Abdolrasoul Rangrazi, Parastoo Namdar, Farzaneh Lal Alizadeh   +4 more
doaj   +1 more source

U.S. Employment Situation Summary: June 2012 [PDF]

, 2012
Unemployment rate largely unchanged, youth, veterans, minorities and those with less education disproportionately ...

core  

Characterization of Active Main Belt Object P/2012 F5 (Gibbs): A Possible Impacted Asteroid [PDF]

, 2012
In this work we characterize the recently discovered active main belt object P/2012 F5 (Gibbs), which was discovered with a dust trail > 7' in length in the outer main belt, 7 months prior to aphelion.
Bauer, J. M., Kramer, E. A., Mainzer, A. K., Masiero, J. R., Stevenson, R.   +4 more
core   +3 more sources

Children’s and adolescents’ rising animal-source food intakes in 1990–2018 were impacted by age, region, parental education and urbanicity [PDF]

, 2023
Victoria Miller, Patrick Webb, Frederick Cudhea, Jianyi Zhang, Julia Reedy, Peilin Shi, Josh Erndt‐Marino, Jennifer Coates, Renata Micha, Dariush Mozaffarian, Murat Baş, Jemal Haidar, Suhad Abumweis, Anand Krishnan, Puneet Misra, Nahla Chawkat Hwalla, Chandrashekar Janakiram, Nur Indrawaty Liputo, Abdulrahman O. Musaiger, Farhad Pourfarzi, Iftikhar Alam, Karin DeRidder, Céline Termote, Anjum Memon, Aida Turrini, Elisabetta Lupotto, Raffaela Piccinelli, Stefania Sette, Karim Anzid, Marieke Vossenaar, Paramita Mazumdar, Ingrid Rached, Alicia Rovirosa, María Elisa Zapata, Tamene Taye Asayehu, Francis Oduor, Julia Boedecker, Lilian Aluso, Johana Ortíz‐Ulloa, J.V. Meenakshi, Michelle Alessandra de Castro, Giuseppe Grosso, Anna Waśkiewicz, Umber S. Khan, Anastasia Thanopoulou, Reza Malekzadeh, Neville Calleja, Marga C. Ocké, Zohreh Etemad, Mohannad Al Nsour, Lydiah M. Waswa, Eha Nurk, Joanne E Arsenault, Patricio López‐Jaramillo, Abla Mehio Sibai, Albertino Damasceno, Carukshi Arambepola, Carla Lopes, Mílton Severo, Nuno Lunet, Duarte Torres, Heli Tapanainen, Jaana Lindström, Suvi Μ. Virtanen, Cristina Palacios, Eva Roos, Imelda Angeles‐Agdeppa, Josie Desnacido, Mario V. Capanzana, Anoop Misra, Ilse Khouw, Swee Ai Ng, Edna Gamboa Delgado, Mauricio Caballero, Johanna Otero, Hae‐Jeung Lee, Eda Köksal, Idris Guessous, Carl Lachat, Stefaan De Henauw, Ali Reza Rahbar, Alison Tedstone, Androniki Naska, Angie Mathee, Annie Ling, Bemnet Tedla, Beth Hopping, Brahmam Ginnela, Catherine Leclercq, Charmaine Duante, Christian Haerpfer, Christine Hotz, Christos Pitsavos, Colin D. Rehm, Coline van Oosterhout, Corazon Cerdeña, Debbie Bradshaw, Dimitrios Trichopoulos, Dorothy Gauci, Dulitha Fernando   +99 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Ectopic premolar tooth in the sigmoid notch [PDF]

, 2016
Impaction of a mandibular premolar is relatively uncommon. Ectopic placement is more unusual and there has been no discussion in the literature of an ectopic mandibular premolar in the coronoid process. In this case report, we present an impacted ectopic
Akgul, Hayati Murat, Bayrakdar, Ibrahım Sevki, Torenek, Kubra   +2 more
core   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source