Concepção De Um Sistema De Gestão Ambiental Aplicável Às Unidades Das Forças Armadas [PDF]
, 2008 A protecção do meio Ambiente e a utilização racional dos recursos naturais têm assumido um papel cada vez mais relevante na Gestão das Organizações, fruto, principalmente, da crescente consciencialização das fragilidades do meio Ambiente e da ...
Cordeiro, Francisco
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Pegada de carbono da produção de carne bovina no Nordeste de Portugal: comparação entre dois sistemas produtivos [PDF]
, 2017 A indústria cárnica gera emissões elevadas de gases de efeito estufa (GEE) para a atmosfera. O setor pecuário mundial, por exemplo, é responsável por aproximadamente 18% das emissões globais dos gases do efeito estufa como CO2, N2O e CH4.
Dal Bosco, Tatiane +4 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Mettre en œuvre une nouvelle politique de protection de la biodiversité en forêt, que vont faire les acteurs ? Stakeholder reactions to new policies for forest-biodiversity protection [PDF]
Sciences, Eaux & Territoires, 2010 Déterminer le comportement des acteurs en charge de mettre en œuvre les politiques, prévoir la réaction des publics et usagers impactés par leurs mesures, deviennent un atout précieux pour le décideur.
Jean-Paul Bousset, Claire Choquet, Catherine Macombe et Monique Bouchaud
doaj
[Assessment of the effect of the COVID-19 health crisis on the aerobic capacities of healthy patients. Analysis of the effort tests of the patients of the sports medicine services of the Angers UHC and the Cholet HC between May 2018 and May 2021]. [PDF]
Sci Sports, 2023 Barbe G, Bickert S.
europepmc +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Millora de competències transversals mitjançant el treball col·laboratiu amb wikis [PDF]
, 2017 L'aplicació de wikis en el desenvolupament de treballs col·laboratius és una eina virtual que millora la gestió de la informació científica que es recull i en facilitat la disponibilitat a tots els membres del grup.
Aulinas Juncà, Meritxell +4 more
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