Results 191 to 200 of about 2,552,887 (339)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Prevalence of Mandibular Third Molar Impaction, Associated Pathologies, and Correlation With Temporomandibular Joint Morphology in a Hospital-Based Spanish Cohort: A Panoramic Radiography Study. [PDF]

Int J Dent
Assiri HA, Estrugo-Devesa A, Egido-Moreno S, Llabrés XR, Hameed MS, Alqarni A, López-López J.   +6 more
europepmc   +1 more source

Functional Analysis of the Lactococcus lactis galU and galE Genes and Their Impact on Sugar Nucleotide and Exopolysaccharide Biosynthesis

, 2001
Ingeborg C. Boels, Ana Ramos, Michiel Kleerebezem, Willem M. de Vos   +3 more
openalex   +1 more source

Functional response of plant communities to clearcutting: management impacts differ between forest vegetation zones [PDF]

, 2014
Buntarou Kusumoto, Takayuki Shiono, Mai Miyoshi, Ryo Maeshiro, Shinjiro Fujii, Timo Kuuluvainen, Yasuhiro Kubota   +6 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Rectal Impaction of a Migratory Duck Bone After 72 Asymptomatic Hours: A Defused Time Bomb. [PDF]

Clin Case Rep
Cheng Z, He J, Chen Y, Ju H, Wang K, Wang Y, Wang H, Shen Y.   +7 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Unlocking predictive genetic factors with artificial intelligence: relationship between dental impaction and hypodontia evaluated via association-rule algorithms: a case-control study. [PDF]

Saudi Dent J
Alhazmi N, Alaqla A, Almuzzaini B, Aldrees M, Alnaqa G, Almasoud F, Thomas SK, Alshamlan H.   +7 more
europepmc   +1 more source

The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy

, 2011
Bram Ramaekers, Manuela Joore, Janneke P.C. Grutters, Piet van den Ende, Jos de Jong, Ruud Houben, Philippe Lambin, Miranda E.M.C. Christianen, Ivo Beetz, Madelon Pijls-Johannesma, Johannes A. Langendijk   +10 more
openalex   +2 more sources