Results 251 to 260 of about 40,291 (312)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Expert consensus on the management of third molar health. [PDF]

Int J Oral Sci
Sun R, Xu Y, Wu Y, Pan J, Zhou C, Zou D, Wang Y, Xue Y, Cai Y, Cui N, Hu K, Zhang W, Han B, Zhou Q, Chen S, Tang H, Wang L, Wang X, Li B, Ma Z, Xu X, Li Z, Wu Y, Sun G, Zhu F, Hu Y, Gao K, Zhou J, Zhao J.   +28 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Genetic Aspects of Dental Impaction: A Scoping Review. [PDF]

Genes (Basel)
Oliva-Ferrusola E, Baus-Domínguez M, Torres-Lagares D, Serrera-Figallo MA.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The impacts of nanotechnology

Nanotechnology Perceptions, 2011
openaire   +1 more source

Nebulized-Swallowed Albuterol for the Treatment of Food Impaction in Pediatric Patients with Eosinophilic Esophagitis: A Novel Nonendoscopic Approach. [PDF]

J Pediatr Clin Pract
Gunasekaran TS, Gorla K, Berman J, Bhardwaj V.   +3 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

An investigation of the prevalence of impacted teeth in Kabul, Afghanistan: A retrospective cross-sectional study. [PDF]

Medicine (Baltimore)
Ahmadi SU, Ehsan H, Ehsan H, Fayaz Y, Wali S, Fahimi R, Joya M, Barakati T, Humkar O, Shadab H, Yaqubi I.   +10 more
europepmc   +1 more source

MSX1 and PAX9 Polymorphisms and Their Association With Lateral Incisor Morphology in Patients With Maxillary Canine Impaction. [PDF]

Med Sci Monit
Todorović A, Filipović G, Stefanović N, Vujić S, Todorović K, Mitić V, Janošević P, Radojičić J, Šćepan I.   +8 more
europepmc   +1 more source