Results 161 to 170 of about 2,558,373 (316)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Dive tourism and local communities: active participation or passive impacts? Case studies from Malaysia. [PDF]

For many Less Developed Countries international tourism has long been considered a driver for economic development (OECD, 1967). However, tourism has also been heavily criticised for its negative environmental and cultural impacts and significant ...
Daldeniz, Bilge, Hampton, Mark P.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Revealing Hidden Biodiversity Footprints Embedded in Global Mining Supply Chains. [PDF]

Environ Sci Technol
Yu Y, Wang S, Cabernard L, Pfister S.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A GLOBAL MODEL OF CLIMATE CHANGE IMPACTS ON TIMBER MARKETS

Several papers have now estimated the impact of climate change on national timber markets, but few studies have measured impacts globally. Further, the literature on impacts has focused heavily on changes in productivity and has not integrated movements ...
Sohngen, Brent, Sedjo, Roger A., Mendelsohn, Robert   +2 more
core  

État de la situation sur les impacts sociétaux de l'intelligence artificielle et du numérique - 2024

Obvia. (2024). État de la situation sur les impacts sociétaux de l’intelligence artificielle et du numérique - 2024. https://doi.org/10.61737/CFRT3613 Axe Santé durable Sous la responsabilité de : Martin Cousineau et Marie-Pierre Gagnon En collaboration

core   +1 more source

Perceived impacts of extreme heat on health and livelihoods in Nigeria. [PDF]

Environ Res Health
Olaitan AM, Egbogah I, Osuolale KA, Esiaba C, Mason LR, Ekenga CC.   +5 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decision-making framework for response and management of environmental disasters (FRaMED). [PDF]

Environ Manage
Bragg WK, Bell CA, Lonhart SI.
europepmc   +1 more source