Turkish Version of Grief Impairment Scale: Adaptation, and Psychometric Properties
Psikiyatride Güncel YaklaşımlarObjective: Grief Impairment Scale was developed as a rapid and flexible tool for assessing the biopsychosocial impairment associated with grief. This study aimed to evaluate the psychometric properties of the Turkish version of the scale.
Buket Şimşek Arslan +1 more
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Severe vision impairment is associated with cumulative social risk among adults in Puerto Rico: a population-based study. [PDF]
Front Public HealthBusquets MA +4 more
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Vision impairment and cognitive function in Chinese older adults with diabetes: multiple mediating effects of social participation and perceived control. [PDF]
Front Public HealthYin Y, Wang T, Xu T, Liu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Intrinsic capacity impairment and incident dementia across three population-based cohorts: a harmonized individual participant data analysis. [PDF]
J Nutr Health AgingZhou Y, Guo Y.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Risk of cognitive disorders in patients with primary Sjögren's disease: data from Korean Health Insurance Service. [PDF]
RMD OpenMin HK, Lee SW, Kim S, Kim G, Moon SJ.
europepmc +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source