Results 231 to 240 of about 1,768,108 (318)

Prevalence of dual sensory impairment in Australia: a nationally representative population-based survey of Indigenous and non-Indigenous Australians. [PDF]

Lancet Reg Health West Pac
Gopinath B, Macken O, Kha R, Low G, Kapucu Y, Newall J, Waddell C, Fricke T, Yang E, Indrakumar M, Tang D, Turner A, Keay L, Liew G, Mitchell P.   +14 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Preference-based scoring algorithm to estimate societal utilities based on the patient-reported experience of cognitive impairment in schizophrenia (PRECIS) instrument. [PDF]

Qual Life Res
Hoogendoorn M, Santi I, Sussex AK, Aggio D, Wang J, Lloyd A.   +5 more
europepmc   +1 more source

Cognitive impairment

Neurosciences, 2016
openaire   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Imaging Biomarkers of Cognitive Impairment in Sarcopenia: A Narrative Review. [PDF]

Int J Gen Med
Lei WX, Zhu JJ, Jiang YT, Peng XH, Sun HR, Tan J, Zhou XH, Huang MX, Lei H, Zhao H.   +9 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Association between intrinsic capacity and dementia risk in older Mexicans. [PDF]

Alzheimers Dement
López-Teros MT, Yeverino-Castro SG, Yocupicio-Medrano F, Mimenza-Alvarado AJ, Gutiérrez-Robledo LM, Bello-Chavolla OY, Aguilar-Navarro SG.   +6 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source