Results 41 to 50 of about 1,961,883 (258)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Reversal learning is influenced by cognitive flexibility and develops throughout early adolescence

npj Science of Learning
Learning behavioural responses and adapting them based on feedback is crucial from a young age, continuing to develop into young adulthood. This study examines the development trajectory and contributing factors from childhood to adulthood using a ...
Christoph Bamberg, Sarah Weigelt, Klara Hagelweide   +2 more
doaj   +1 more source

Comparison of Two Manual Therapy Techniques in Patients with Carpal Tunnel Syndrome: A Randomized Clinical Trial

Caspian Journal of Internal Medicine, 2020
Background: Manual therapy techniques are part of physiotherapy treatment of carpal tunnel syndrome (CTS) which are classified into two groups including nerve mobilization and mechanical interface mobilization.
Ghadam Ali Talebi, Payam Saadat, Yahya Javadian, Mohammad Taghipour   +3 more
doaj  

El acceso a tecnologías de asistencia por parte de personas con discapacidad: una mirada crítica en la perspectiva de la “inclusión productiva”

Revista Crítica de Ciências Sociais, 2023
This article argues that the relationship between technology and access is paradoxical, and that although technology is often associated with access and integration, it can also isolate people, creating unique forms of social exclusion.
Alexander Benavides-Franco, Nohemy Marcela Bedoya-Ríos, Edwin Gerardo Cruz-Daza   +2 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Predictive factors and risk and protection groups for loneliness in older adults: a population-based study

BMC Psychology
Background Loneliness is considered a public health problem, particularly among older adults. Although risk factors for loneliness have been studied extensively, fewer studies have focused on the protected and risk groups that these factors configure ...
Pedro Montejo Carrasco, David Prada Crespo, Ana Isabel Reinoso García, Monserrat Lozano Ibáñez, Borja Montejo Rubio, Mercedes Montenegro-Peña   +5 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

ADHD: the impact when not diagnosed TDAH: o impacto da ausência do diagnóstico

Jornal Brasileiro de Psiquiatria, 2008
ADHD is a highly prevalent disorder in childhood with social, academic and familial difficulties when not diagnosed and treated correctly. The aim of this case report is to demonstrate the impairment of ADHD among generations of the same family.O TDAH é ...
Isabella de Souza, Paulo Mattos, Camila Pina, Didia Fortes   +3 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Beyond the Buzzword: Unpacking ‘Special Needs’ in Denmark

Scandinavian Journal of Disability Research
The term ‘special needs’ encompasses various definitions of what is considered ‘special’ for children with functional variations. These definitions reflect societal views shaped by politics, economics, governance, and knowledge, all of which ...
Pia Ringø, Emil Søbjerg Falster
doaj   +1 more source