Results 61 to 70 of about 28,579 (259)
Yuanzineng kexue jishu, 2022 The beam calibration results are affected by the impedance of the calibration device. If impedance matching is not maintained, reflected signals would be generated, which would lead to the superposition of reflected signals and excitation signals ...
BAI Haitao;WANG Yi;HE Xiaozhong;LIAO Shuqing;SHI Jinshui
doaj
Paper-based methodology for investigation of triboelectric nanogenerators
Energy Reports, 2019 Triboelectric nanogenerators (TENGs) have been investigated as a promising methodology to harvest mechanical energy into electricity. The matching impedance and the transient property of TENGs are important for their practical application.
Zhiyuan Zhu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Fast impedance matching for the ion cyctron resonance heating system based on capacitors at the EAST tokamak [PDF]
EPJ Web of ConferencesThis paper presents an impedance matching system based on real-time feedback control, designed to address impedance mismatching issues in radio frequency (RF) systems.
Guo Yaoyao +5 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
ActuatorsThis paper proposes a robust impedance controller to address the performance limitations of mechanical impedance rendering in robotic joints, enabling stable interaction with passive environments.
Nianfeng Shao +3 more
doaj +1 more source
Three-Dimensional Package Design for Electro-Absorption Modulation Laser Array
IEEE Photonics Journal, 2016 We report a new 3-D package design technique in this paper. Based on this technique, a 3-D RF impedance matching circuit used in the packaging of electroabsorption modulation laser (EML) array is achieved, which has the characteristics of low electrical ...
Zhike Zhang +7 more
doaj +1 more source