Results 91 to 100 of about 347,752 (281)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Evaluation of a multi-point method for determining acoustic impedance [PDF]

An investigation was conducted to explore potential improvements provided by a Multi-Point Method (MPM) over the Standing Wave Method (SWM) and Two-Microphone Method (TMM) for determining acoustic impedance.
Jones, Michael G., Parrott, Tony L.
core   +1 more source

Dielectric measurement based microstrip transmission line [PDF]

, 2019
The measurement of complex dielectric properties of materials at radio frequency is very important especially in the research fields, such as material science, microwave circuit design, absorber development, biological research, etc.
Ikhsan, Fatin Hamimah
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Analysis of the impact of measurement on the impedance stability of HVDC grids

Frontiers in Energy Research
The rapid advancement of power electronics technology has led to the development of more flexible DC transmission systems, revealing the issue of oscillations.
Dawei Zhao, Zaiyu Chen, Jing Bu, Qun Li, Qiang Li, Xiaohu Rong   +5 more
doaj   +1 more source

Complex Impedance as a Diagnostic Tool for Characterizing Thermal Detectors

, 2004
The complex ac impedance of a bolometer or microcalorimeter detector is easily measured and can be used to determine thermal time constants, thermal resistances, heat capacities, and sensitivities.
Vaillancourt, John E.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Beam-based impedance measurement of HL-LHC low-impedance collimators

Physical Review Accelerators and Beams
The objective of the High Luminosity Large Hadron Collider (HL-LHC) upgrade is to attain an instantaneous luminosity that is 5 times greater than the design value of the LHC.
A. Kurtulus, D. Amorim, N. Biancacci, X. Buffat, L. Giacomel, J. Leuthold, N. Mounet, S. Redaelli, J. Smajic   +8 more
doaj   +1 more source

Design of a CMOS closed-loop system with applications to bio-impedance measurements [PDF]

, 2010
This paper proposes a method for impedance measurements based on a closed-loop implementation of CMOS circuits. The proposed system has been conceived for alternate current excited systems, performing simultaneously driving and measuring functions ...
Rueda Rueda, Adoración, Yúfera García, Alberto   +1 more
core