Results 91 to 100 of about 178,149 (329)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

AC-Side Impedance-Based Stability Assessment in Grid-Forming Modular Multilevel Converters

open access: yesIEEE Access
Grid-forming converters can emulate the behavior of a synchronous generator through frequency droop control. The stability of grid-forming modular multilevel converters can be studied via the impedance-based stability criterion. This paper presents an ac-
Mehrdad Nahalparvari   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

General Geometric Fluctuation Modeling for Device Variability Analysis

open access: yes, 2015
The authors propose a new modeling approach based on the impedance field method (IFM) to analyze the general geometric variations in device simulations.
Choi, Woosung   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Compact Quasi-Static Model for Magnetic Dipole Resonance in Metallic Nanoparticles With Large Radii

open access: yesIEEE Access
Magnetic resonance in metallic nanoparticles has garnered significant attention from scientists for its promising applications in medical diagnostics, data storage technologies, and the development of advanced metamaterials.
Ahsan Irshad   +4 more
doaj   +1 more source

Analogy electromagnetism-acoustics: Validation and application to local impedance active control for sound absorption

open access: yes, 1998
An analogy between electromagnetism and acoustics is presented in 2D. The propagation of sound in presence of absorbing material is modeled using an open boundary microwave package.
Furstoss, M.   +2 more
core   +2 more sources

Reflectance-Based Foster Impedance Data Modeling

open access: yesFrequenz, 2007
A reflectance-based method is presented to model a set of given Foster impedance data as a lossless singly terminated two-port consisting of lumped-elements in short or open termination. The basis of the new method rests on the interpolation of the given data as a realizable bounded-real (BR) reflection function.
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy