Results 121 to 130 of about 178,149 (329)

Model-Based Reinforcement Learning Variable Impedance Control for Human-Robot Collaboration [PDF]

open access: bronze, 2020
Loris Roveda   +6 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Stability analysis and high frequency resonance suppression of MMC model predictive control

open access: yes电力工程技术
Model predictive control (MPC) is applied in modular multilevel converter (MMC) control due to its advantages of fast response and simple modeling. However, previous research has not addressed high-frequency resonance suppression. Firstly, a mathematical
Xuewei QIAN   +4 more
doaj   +1 more source

Circuital and Numerical Models for Calculation of Shielding Effectiveness of Enclosure with Apertures and Monitoring Dipole Antenna Inside [PDF]

open access: yes, 2013
In this paper, circuital and numerical models of metal In this paper, circuital and numerical models of metal enclosure with apertures are considered for the purpose of accurate shielding effectiveness calculation.
B. Milovanović   +3 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Harmonic Impedance Model of Multiple Utility-Interactive Multilevel Photovoltaic Inverters [PDF]

open access: gold, 2022
Christian A. Rojas   +4 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Application of a self-designed inspiratory impedance threshold device in cardiopulmonary resuscitation in three porcine models of cardiac arrest [PDF]

open access: gold, 2019
Chao Li   +10 more
openalex   +1 more source

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