Results 81 to 90 of about 3,876,241 (284)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Electrochemical Evaluation and Phase-related Impedance Studies on Silicon–Few Layer Graphene (FLG) Composite Electrode Systems

open access: yesScientific Reports, 2018
Silicon-Few Layer Graphene (Si-FLG) composite electrodes are investigated using a scalable electrode manufacturing method. A comprehensive study on the electrochemical performance and the impedance response is measured using electrochemical impedance ...
Qianye Huang   +4 more
doaj   +1 more source

Early Altered Cells Health Status Detection via Label Free Impedance and Broadband dielectric Spectroscopy

open access: yes, 2021
Human cells are able to respond to applied electrical signals and their response is different according to cell health status. In this framework, the electrical bio-impedance can be sensitive tools to monitor cellular health status in addition to other ...
Perna G.   +5 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Micro-impedance cytometry

open access: yes, 2010
Electrical impedance spectroscopy is a non-invasive and label free technique that allows for rapid counting and characterisation of particles in suspension based on their response to applied AC potentials. In recent years, lab-on-a-chip technologies have
Bernabini, Catia
core   +2 more sources

Four-Wire Impedance Spectroscopy on Planar Zeolite/Chromium Oxide Based Hydrocarbon Gas Sensors

open access: yesSensors, 2007
Impedometric zeolite hydrocarbon sensors with a chromium oxide intermediatelayer show a very promising behavior with respect to sensitivity and selectivity. Theunderlying physico-chemical mechanism is under investigation at the moment.
Ralf Moos   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Design and evaluation of a portable device for the measurement of bio-impedance-cardiograph

open access: yes, 2022
S.65-72Electrical impedance of biological matter is known as electrical bio-impedance or simply as bio-impedance. Bio-impedance devices are of great value for monitoring the pathological and physiological status of biological tissues in clinical and home
Kanoun, O., Shi, Q., Heinig, A.
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

A Review on Electrical Impedance Tomography Spectroscopy

open access: yesSensors, 2020
Electrical Impedance Tomography Spectroscopy (EITS) enables the reconstruction of material distributions inside an object based on the frequency-dependent characteristics of different substances.
Juliana Padilha Leitzke, Hubert Zangl
doaj   +1 more source

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