Scalable, High-Density Expansion of Human Mesenchymal Stem Cells on Microcarriers Using the Bach Impeller in Stirred-Tank Reactors. [PDF]
Wyrobnik TA +5 more
europepmc +1 more source
Dynamic Evolution and Transformative Trends in the Consumer Market: A Technology Paradox Perspective
ABSTRACT The consumer market is defined by tensions arising from the clash between technological advancement and consumer psychology. Current research lacks a unifying framework to explain these contradictions. Addressing this gap, we introduce a conceptual model based on technology paradox theory, which maps the dynamic process from antecedents ...
Chanaka Jayawardhena +3 more
wiley +1 more source
Engineering Characterization of Small-Scale Bioreactors for Large-Scale hiPSC Production. [PDF]
Vicente P +10 more
europepmc +1 more source
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma +14 more
wiley +1 more source
Burst agitation rate promotes sustained semicontinuous cultivation of filamentous fungi in stirred tank reactors. [PDF]
Lochlainn CÓ, Cerrone F, O'Connor KE.
europepmc +1 more source
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo +14 more
wiley +1 more source
Open-source tubing-free impeller pump platform for controlled recirculating fluid flow for microfluidics and organs-on-chip. [PDF]
Cook SR +3 more
europepmc +1 more source
Psychiatric Comorbidity, Tic Severity and Quality of Life in Adults with Tourette's Syndrome
Abstract Background Psychiatric comorbidities are common in adults with Tourette's Syndrome (TS), and appear to influence both tic severity and quality of life (QOL). Objective To assess the association between psychiatric comorbidities, tic severity and QOL in TS.
Andreas Hartmann +9 more
wiley +1 more source
Scale-Up Strategy Focused on Hydrodynamic Stress for Mammalian Cell Culture Established by a Dry-Wet Approach. [PDF]
Kenmoku H +5 more
europepmc +1 more source
Abstract Background The Huntington's Disease Behavioral Questionnaire (HD‐BQ) captures behavioral symptoms arising from cognitive, psychiatric, and functional domains. Recognizing the high prevalence of anosognosia in HD, the HD‐BQ incorporates patient‐ and companion‐reported versions.
Siena Rigatuso +5 more
wiley +1 more source

