Results 81 to 90 of about 27,216 (302)
Open Physics, 2023 Warranty can improve customer satisfaction and increase product sales, but it will bring additional economic burden to manufacturers, so making reasonable warranty decisions is particularly important. The current research focuses more on the interests of
Cheng Junkai
doaj +1 more source
, 1938 We consider a distributed detection system under communication constraints, where several peripheral nodes observe a common phenomenon and send their observations to a fusion center via error-free but rate-constrained channels. Using the minimum expected
Jalden, Joakim, Tarighati, Alla
core +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Optimizing the integrated economic production quantity for a stochastically deteriorating production system under condition-based maintenance [PDF]
, 2017 This paper proposes a new integrated economic production quantity (EPQ) and condition-based maintenance (CBM) model for a stochastically deteriorating production system. Inspections are performed periodically to measure the real time degradation.
Aghezzaf, El-Houssaine +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Preventive maintenance policy on leasing by considering the usage rate
MATEC Web of Conferences, 2018 The needs of the consumers about the functionality of a product and increase maintenance costs of equipment caused the prices of products and treatments to be expensive. Therefore, the company considers the lease rather than buy it.
Jufriyanto Moh. +2 more
doaj +1 more source
Mathematics, 2019 This study considers the effects of a machine breakdown, inspection, and partial backordering for deteriorating items. Most industries try to reduce facility unavailability by implementing a regular inspection and preventive maintenance since there is a ...
K.Y. Kung +3 more
doaj +1 more source