Results 81 to 90 of about 1,597,070 (284)
EnergiesMaintaining aging equipment is essential for ensuring the reliability and performance of power substations, which are critical components of electric power systems.
Carlos Alberto Murad +3 more
doaj +1 more source
Mathematics, 2019 This study considers the effects of a machine breakdown, inspection, and partial backordering for deteriorating items. Most industries try to reduce facility unavailability by implementing a regular inspection and preventive maintenance since there is a ...
K.Y. Kung +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Optimization of joint preventive maintenance strategy for two-dimensional warranty equipment
AIP AdvancesThe implementation of a joint preventive maintenance (JPM) strategy for complex product systems can significantly enhance maintenance effectiveness during the warranty period, alleviate the manufacturer’s warranty burden, and empower users with greater ...
Enzhi Dong +3 more
doaj +1 more source
Applied SciencesThe reliability of traction systems in urban rail transit vehicles is critical to safe and efficient operations. However, existing reliability assessment methods face challenges such as state space explosion, computational complexity, and difficulties in
Junjie Zhang +3 more
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Optimal maintenance of multi-component systems: a review [PDF]
In this article we give an overview of the literature on multi-component maintenance optimization. We focus on work appearing since the 1991 survey "A survey of maintenance models for multi-unit systems" by Cho and Parlar.
Dekker, R., Nicolai, R.P.
core
, 2014 Part 2: Knowledge Discovery and SharingInternational audienceIn this paper, the considered system corresponds to a specific equipment proposed for leasing. This equipment is leased to several lessees who use it under various working conditions.
Schutz, Jérémie, Jérémie Schutz
core +1 more source
Decline and repair, and covariate effects [PDF]
, 2015 The failure processes of repairable systems may be impacted by operational and environmental stress factors. To accommodate such factors, reliability can be modelled using a multiplicative intensity function.
Scarf, PA, Scarf, Philip, Wu, Shaomin
core +1 more source