Results 61 to 70 of about 10,104 (251)
AppliedMathThis model extends the classical economic production quantity (EPQ) model to address the complexities within a two-echelon supply chain system. The model integrates the cost of raw materials necessary for production and takes into account the presence of
Kapya Tshinangi +2 more
doaj +1 more source
Operations Research Perspectives, 2019 We present inventory models to schedule an imperfect manufacturing process where a proportion of the items are defective. The proportion is known; and the production is followed by a 100% inspection.
Muhammad Al-Salamah
doaj +1 more source
Advances in Industrial and Manufacturing Engineering, 2020 Unreliable conditions and process deterioration of machines are the major issues in several manufacturing systems. These issues not only affect the production schedules but also affect the product quality significantly.
S. Ganesan, R. Uthayakumar
doaj +1 more source
Development of Integrated Maintenance-Quality Policy according to imperfect quality item produced
IFAC-PapersOnLine, 2016 In this paper, we develop integrated models joining non-quality effects and preventive maintenance policy We consider a randomly failing manufacturing system producing one type of product. We note that the output product can be conform or non-conform. In order to reduce random failures of our manufacturing system, a preventive maintenance (PM) policy ...
Gouiaa-Mtibaa, Amal +3 more
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source