Results 161 to 170 of about 733,404 (291)

Availability of a system maintained through several imperfect repairs before a replacement or a perfect repair

open access: yes
Employing the Fourier transformation technique, we find the availability of a system maintained through several imperfect repairs before a replacement or a perfect repair is allowed. We obtain exact expressions for the availability when both lifetime and
Biswas, Atanu, Sarkar, Jyotirmoy
core  

Determination of the optimal periodic maintenance policy under imperfect repair assumption

open access: yes, 2014
An appropriate maintenance policy is essential to reduce expenses and risks related to repairable systems failures. The usual assumptions of minimal or perfect repair at failures are not suitable for many real systems, requiring the application of ...
Maria Luiza Guerra de Toledo
core  

Improvement of precise large-fragment deletion with a versatile nuclease prime editor. [PDF]

open access: yesCell Discov
Li X   +12 more
europepmc   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali   +14 more
wiley   +1 more source

On engineering reliability concepts and biological aging [PDF]

open access: yes
Some stochastic approaches to biological aging modeling are studied. We assume that an organism acquires a random resource at birth. Death occurs when the accumulated dam-age (wear) exceeds this initial value, modeled by the discrete or continuous random
Maxim S. Finkelstein
core  

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto   +12 more
wiley   +1 more source

Optimal times for software release when repair is imperfect

open access: yes
The determination of the optimal release time for a new piece of software is of primary importance in the process of software development. We study a model where initially there are N faults in the software each with failure detection rate [lambda](t ...
Ní Chuív, Nóra, Boland, Philip J.
core  

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

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