Results 211 to 220 of about 74,497 (338)
Considerations for drug trials in hypertrophic cardiomyopathy
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source
ABSTRACT The current research focused on how competing narratives (i.e., dominant and resistance narratives) are endorsed among low‐status group members, through the case of the US military base issue in Okinawa, Japan. Specifically, we explored patterns of Okinawans’ narrative endorsement (i.e., dominant and resistance narratives surrounding the ...
Maho Aikawa, Andrew L. Stewart
wiley +1 more source
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli +43 more
wiley +1 more source
ABSTRACT Risk‐based seismic assessments using demand curves that provide mean annual exceedance rates for various system demand levels are increasingly being adopted. Such assessments combine the seismic hazard curve with fragility functions for each demand level, serving as a basis to quantify the average annual losses from system damage. Constructing
Zeyad Khalil +2 more
wiley +1 more source
Reasoning in Life: Values and Normativity in Georges Canguilhem. [PDF]
Vissio G.
europepmc +1 more source
ABSTRACT Nonstructural components (NSCs) installed in large‐span reticular structures were frequently severely damaged during earthquakes, even when the primary structure remained intact. Existing seismic design specifications for NSCs were predominantly developed for upright structures such as multi‐storey buildings and offer no guidance for reticular
Xudong Zhi +6 more
wiley +1 more source
Possible Racial Disparities in the Diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). [PDF]
Jones CL, Younger J.
europepmc +1 more source
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang +5 more
wiley +1 more source

