Results 91 to 100 of about 116,580 (263)

RCT on the survival of implant-supported and tooth-implant-supported fixed restorations [PDF]

Clinical Oral Implants Research, 2017
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Tooth-implant-supported fixed prostheses

Current Research in Dental Sciences, 2023
Cansu KURTOĞLU, Neşet Volkan ASAR
doaj   +1 more source

Assessment Of Intraoral Scanning For Three-Unit Implant-Supported Bridges

International Dental Journal
Aim or purpose: To evaluate the dimensional accuracy of intraoral scanning (IOS) for three-unit implant-supported fixed prostheses in posterior regions and compare it with conventional impression methods to determine its clinical applicability. Materials
Shuobo Fang, Zhong Xingjian, Wu Xueying, Shen Yuyin, Gong Zhicheng   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Mechanical Evaluation of Two Different Zirconia-Reinforced Lithium Silicate Ceramics: A Finite Element Analysis

Current Research in Dental Sciences
Objective: The aim of the study is to evaluate the stress distribution of zirconia-reinforced lithium silicate all-ceramic fixed partial dentures under occlusal loading; in terms of material, restoration, and supporting type.Methods: Six different models
Hüseyin Botsalı, Arzu Atay, Sibel Dikicier, Merve Botsalı   +3 more
doaj   +1 more source

Unilateral implant-supported prosthesis [PDF]

British Dental Journal, 2019
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Questioning the Awareness of Partially Edentulous Patients About Dental Implants and Implant Supported Dental Prostheses

Cyprus Journal of Medical Sciences
BACKGROUND/AIMS: To measure and evaluate the level of awareness of a specific patient population with partial edentulism about dental implants, implant-supported prostheses, and the general treat-ment processes related to these. MATERIALS AND METHODS: A
Elifnur Güzelce Sultanoğlu, Bedirhan Dökülmez, Meryem Hürbağ   +2 more
doaj   +1 more source