Results 131 to 140 of about 2,426,681 (302)

Stress distribution by parafunctional loading on tooth–implant, implant–implant, and tooth–tooth-supported prosthesis: A comparative three-dimensional finite element analysis

open access: yesThe Journal of Indian Prosthodontic Society
Aim: The study’s objective was to evaluate the stress distribution in tooth-implant, implant-implant, and tooth-tooth supported prostheses under parafunctional loading in axial and oblique directions employing a 3D finite element analysis in the ...
P Ambili Ravindran   +5 more
doaj   +1 more source

Restoration of Failing Maxillary Implant-Supported Fixed Prosthesis With Cross Arch Splinted Unilateral Zygomatic Implant: A Clinical Report

open access: yes, 2012
Management of one or more failing distal implants in an implant supported fixed prosthesis in a completely edentulous maxilla creates a challenging situation.
Mariappan Saravanakumar   +2 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Implant-Supported Overdenture Therapy: A 3-to 8-Year Prospective Study

open access: yes, 2000
Inflammatory changes in peri-implant soft tissues and loss of alveolar bone can develop as in periodontal diseases. This clinical phenomena has been described as periimplantitis.
Alptekin, Nilgün   +2 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Implant-supported distal extensions in severely resorbed posterior alveolar ridges [PDF]

open access: yes, 2008
The application of implant-borne rehabilitations in residual alveolar ridges may be restricted by various anatomic conditions, as available bone height and characteristics.
Minoretti, Roger   +2 more
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Implant-supported overdenture, an alternative option for the rehabilitation of a completely edentulous mandibular arch

open access: yesJournal of Oral Research and Review
Edentulism has been a long-standing concern in prosthodontics. Several of the drawbacks of conventional denture therapy have been observed to be addressed by implant therapy nowadays.
Ganesh Ram Kumar Rajapandi   +2 more
doaj   +1 more source

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