Results 201 to 210 of about 9,794,583 (384)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Successful echocardiography-guided medical management of severe early post-implant right ventricular failure in a patient with left ventricular assist device support: a case report [PDF]

, 2023
Shingo Kunioka, Osamu Seguchi, Tasuku Hada, Hiroki Mochizuki, Masaya Shimojima, Takuya Watanabe, Yasumasa Tsukamoto, Naoki Tadokoro, Satoshi Kainuma, Satsuki Fukushima, Tomoyuki Fujita, Hiroyuki Kamiya, Norihide Fukushima   +12 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Digital scanning for complete-arch implant-supported restorations: A systematic review.

The Journal of prosthetic dentistry (Print), 2019
C. Wulfman, A. Naveau, C. Rignon-Bret
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Radiographic evaluation of two different implant-supported prosthesis for theedentulous mandible

, 2020
Mahmoud Eldin, Enas Darwish, Andries Van Der Bilt, M Burgers, F Van Kampen, M Cune, M Andreitolli, J Strub, V Arisan, Z Krabuda, B Piskin, T zdemir, E Benavides, H Rios, S Ganz, M Chreli, D Karasoy, A Kokat, H Ismail, S Yousief, A Mahrous, A Shaban, S Azzeghaiby, S Jeong, B Choi, J Kim, S Ma, A Payne, B Narby, I Bagewitz, B Soderfeldt, R Nidhin, G Vasunni, O Ajay, A Rentsch-Kollar, S Huber, R Mericske-Stern, S Rodrigues, M Mundathaje, M Raju, S Qureshi, M Saleem, R Meshak, A Scarano, J Thomason, S Kelly, A Bendkowski, J Ellis, D Twito, P Sade, C Vasak, G Watzak, A Gahleitner, R Vieira, A Melo, L Budel, J Gama, I De, Mattias Sartori, G Thom, P Warin, P Rungsiyakull, C Rungsiyakull, K Khong   +63 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Case Series on Implant Supported Overdenture Prosthesis

Sevgi Öğüt, Nuray Zulkadir Ergin, Mehmet Ergin   +2 more
openalex   +2 more sources