Results 171 to 180 of about 2,028,540 (336)
INTRATESTICULAR IMPLANTATION OF THE FLEXNER-JOBLING RAT CARCINOMA [PDF]
, 1916 William H. Woglom
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Migration of Spleen Cells from Subcutaneous Implantation Sites [PDF]
, 1958 Věra Hašková, N Mitchison
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The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Bekämpfung der Ausfallserscheinungen nach Thymektomie bei Xenopus laevis Daudin durch Implantation von Dauertabletten aus juvenilem Säuger-Thymus [PDF]
, 1955 J. W. Harms
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Peri-implant health and disease. A systematic review of current epidemiology.
Journal of Clinical Periodontology, 2015 Jan Derks, C. Tomasi
semanticscholar +1 more source