Results 51 to 60 of about 1,984,414 (297)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effect of plaque accumulation and occlusal overload on peri-implant bone loss

Journal of Biological Research, 2017
This paper presents a case report where the influence of plaque accumulation and overload on a dental implant was observed. The patient presented crown loss on one implant affected by peri-implant bone resorption and gingival inflammation associated with
Elena Dellepiane, Maria Menini, Paolo Canepa, Paolo Pera   +3 more
doaj   +1 more source

Failure rates and factors associated with infrazygomatic crestal orthodontic implants - A prospective study

Journal of Oral Biology and Craniofacial Research, 2023
Objective: Infrazygomatic crestal (IZC) implants have gained increased popularity over the past few years. Hardly any studies have been done to assess the rate and reasons for failure of IZCs.
Gauri Gill, Keerthan Shashidhar, M.N. Kuttappa, Dhyan Kushalappa P B, Gautham Sivamurthy, Soham Mallick   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Immediate dental implants: insights into early and late failures from a large-scale Chinese cohort

BMC Oral Health
Background Immediate implant placement (IIP) has emerged as a time-efficient therapeutic approach in dentistry, offering advantages such as reduced treatment duration and improved alveolar bone preservation.
Yiyun Yang, Lu Zhou, Xiaomei Hong, Mingfu Ye, Yang Yang, Xiaoling Deng, Mingyan Xu   +6 more
doaj   +1 more source

A Osteointegração em Pacientes Tabagistas: revisão de literatura [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, OdontologiaA osteointegração é um fenômeno que envolve a conexão direta entre osso vital e implantes de titânio, sem crescimento de tecido fibroso na interface osso ...
Petkov, Alexandre
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Failure modes of patellofemoral arthroplasty—registries vs. clinical studies: a systematic review

Acta Orthopaedica, 2019
Background and purpose — Patellofemoral arthroplasty (PFA) has been debated since early studies showed poor implant survival. Recent studies show better results. This review reports failure modes for PFA and investigates differences in data reported from
Nikolaj B Bendixen, Peter W Eskelund, Anders Odgaard   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Outcomes of implant-based oral rehabilitation in head and neck oncology patients—a retrospective evaluation of a large, single regional service cohort

International Journal of Implant Dentistry, 2019
Background The study reports on implant survival outcomes in head and neck cancer patients who received implant-based oral rehabilitation in a regional service centre. Methods A retrospective analysis of implant survival outcomes in patients treated in a
Dominic P. Laverty, Owen Addison, Berhanu A. Wubie, Giseon Heo, Sat Parmar, Timothy Martin, Prav Praveen, David Pearson, David Newsum, Michael Murphy, Geoffrey Bateman   +10 more
doaj   +1 more source