Results 21 to 30 of about 4,601 (167)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Patients’ Socio-Economic Status, Tobacco and Medical History Associated with Implant Failure
Acta Stomatologica Croatica, 2018 Objective: To examine the potential association between patients’ characteristics that experienced implant failure and those who had successful implant treatment.
Georgios S. Chatzopoulos, Larry F. Wolff
doaj +1 more source
Is Penicillin Allergy a Risk Factor for Early Dental Implant Failure? A Systematic Review
Antibiotics, 2021 The prescription of preventive antibiotics in dental implant treatments reduces the incidence of early failures. This study has focused mainly on the influence of amoxicillin, which is contraindicated in penicillin-allergic patients.
Angel-Orión Salgado-Peralvo +9 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
BMC Oral HealthObjectives The purpose of study is to compare early failure rate in patients with self-reported penicillin allergy (SRPA) who take clindamycin after implant surgery with non-allergic patients.
Taha Pergel +5 more
doaj +1 more source
Effect of plaque accumulation and occlusal overload on peri-implant bone loss
Journal of Biological Research, 2017 This paper presents a case report where the influence of plaque accumulation and overload on a dental implant was observed. The patient presented crown loss on one implant affected by peri-implant bone resorption and gingival inflammation associated with
Elena Dellepiane +3 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Immediate dental implants: insights into early and late failures from a large-scale Chinese cohort
BMC Oral HealthBackground Immediate implant placement (IIP) has emerged as a time-efficient therapeutic approach in dentistry, offering advantages such as reduced treatment duration and improved alveolar bone preservation.
Yiyun Yang +6 more
doaj +1 more source
Biomolecules & BiomedicineImplant failure remains a significant challenge in oral implantology, necessitating a deeper understanding of its risk factors to improve treatment outcomes.
Dake Linghu, Danna Zhang, Min Liu
doaj +1 more source