Results 111 to 120 of about 218 (198)

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Mastopexia crescente com implantes de silicone: um estudo longitudinal prospectivo Crescent mastopexy with silicone implants: a longitudinal prospective study

Revista Brasileira de Cirurgia Plástica, 2012
INTRODUÇÃO: Mastopexia periareolar crescente com aumento mamário é uma técnica bem descrita para correção de ptoses mamárias classificadas com graus I e II de Regnault. O objetivo deste estudo é discutir os resultados obtidos utilizando essa técnica, com
Denis Souto Valente, Lauro Aita Carvalho, Rafaela Koehler Zanella   +2 more
doaj  

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), medical treatment of severe systemic compromise: case report. [PDF]

Colomb Med (Cali), 2023
Puerta Sarmiento GE, Modragón I, Echeverri A, Sua LF, Bonilla-Abadía F, Aguirre-Valencia D.   +5 more
europepmc   +1 more source

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus, Christopher J. Bowman, Kimberly C. Brannen, Sarah N. Campion, Laura M. Carlson, Stephan Chalon, Anthony M. DeLise, Claudia Demarta‐Gatsi, Brian P. Enright, Wendy Halpern, Shermaine Mitchell‐Ryan, Vicki Sutherland, Karen Thacker, Kary Thompson, Belen Tornesi, Steven Van Cruchten, Ronald L. Wange, Tacey White, Connie L. Chen   +18 more
wiley   +1 more source

Manejo del seroma crónico en pacientes con implantes de mama en relación con el diagnóstico de linfoma anaplásico de células gigantes [PDF]

Cirugía Plástica, 2019
 Guillermo Ramos-Gallardo,  Rodolfo Luciano Ríos-Lara y López, Jesús Cuenca-Pardo,  Lázaro Cárdenas-Camarena, Livia Contreras-Bulnes,  Estela Vélez Benítez,  Javier Bucio-Duarte, Mario Alberto Pineda-Espinosa, Antonio Ugalde Vitelly, Héctor Manuel Avendaño-Peza   +9 more
openaire   +1 more source

Rate Versus Rhythm Control in a Multimorbid Patient With Tachy–Brady Syndrome: Evaluation of Clinical Outcomes and Pacing Dependency

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case report describes a 77‐year‐old man with multiple comorbidities, including atrial fibrillation, heart failure with mildly reduced ejection fraction, hypertension, diabetes mellitus, and prior coronary artery bypass grafting, who presented with severe hypertension and dyspnoea.
Reem Fakak, Emma Nordahl, Joseph Moutiris   +2 more
wiley   +1 more source

Brazilian Society of Cardiology Guideline on Myocarditis - 2022. [PDF]

Arq Bras Cardiol, 2022
Montera MW, Marcondes-Braga FG, Simões MV, Moura LAZ, Fernandes F, Mangine S, Oliveira Júnior AC, Souza ALAAG, Ianni BM, Rochitte CE, Mesquita CT, de Azevedo Filho CF, Freitas DCA, Melo DTP, Bocchi EA, Horowitz ESK, Mesquita ET, Oliveira GH, Villacorta H, Rossi Neto JM, Barbosa JMB, Figueiredo Neto JA, Luiz LF, Hajjar LA, Beck-da-Silva L, Campos LAA, Danzmann LC, Bittencourt MI, Garcia MI, Avila MS, Clausell NO, Oliveira NA, Silvestre OM, Souza OF, Mourilhe-Rocha R, Kalil Filho R, Al-Kindi SG, Rassi S, Alves SMM, Ferreira SMA, Rizk SI, Mattos TAC, Barzilai V, Martins WA, Schultheiss HP.   +44 more
europepmc   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi   +4 more
wiley   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, Volume 2, Issue 2, June 2026.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang, Li Yang, Ling Wang, Xiao‐Qing Zhang, Jie Wang   +4 more
wiley   +1 more source