Results 91 to 100 of about 1,736,470 (264)

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

Implantes dentales en pacientes de edad avanzada con Diabetes Mellitus: Consideraciones clínicas y resultados

open access: yesCorreo Científico Médico
El presente estudio expresa las consideraciones clínicas y resultados en pacientes  diagnosticados con diabetes mellitus, cuya característica principal es ser una patología crónica multifactorial que afecta a la mayor población entre ellos los adultos ...
Noemí Estefanía Morales Morales   +2 more
doaj  

[Peri-implantitis: current concepts about its etiology, clinical and imaging characteristics. A review]. [PDF]

open access: yesRev Cient Odontol (Lima), 2023
Martínez Gómez JC   +4 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi   +5 more
wiley   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam   +7 more
wiley   +1 more source

Enfoque de ciencia, tecnología y sociedad de la Implantología dental en Camagüey

open access: yesHumanidades Médicas
Existe un auge en la colocación de implantes dentales, dispositivos que mejoran la salud del paciente y restauran su estética y función, lo cual motivó la realización de este trabajo con el objetivo de argumentar la importancia del servicio de implantes ...
Judith Aúcar López   +1 more
doaj  

Preparación pre protética para implantes dentales mediante elevación del seno maxilar. Presentación de un caso clínico

open access: yesRevista Médica Electrónica, 2014
La presencia de pacientes que acuden para su rehabilitación protésica mediante implantes osteointegrados en el maxilar posterior con dificultades es frecuente, debido a una disponibilidad ósea vertical insuficiente causada por la presencia del seno ...
Félix M Blanco Mederos   +1 more
doaj  

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li   +25 more
wiley   +1 more source

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