Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Enfoque de ciencia, tecnología y sociedad de la Implantología dental en Camagüey
Humanidades MédicasExiste un auge en la colocación de implantes dentales, dispositivos que mejoran la salud del paciente y restauran su estética y función, lo cual motivó la realización de este trabajo con el objetivo de argumentar la importancia del servicio de implantes ...
Judith Aúcar López +1 more
doaj
[Stress in an implant-supported unitary fixed partial prosthesis with different materials in the first lower premolar through finite elements]. [PDF]
Rev Cient Odontol (Lima), 2023 Mendez A, Coronado H.
europepmc +1 more source
Immediate loading of implants inserted in postextraction sockets. A 2-year clinical follow-up [PDF]
, 2015 Introducción: El objetivo del presente estudio era mostrar los resultados del tratamiento con implantes dentales insertados después de la extracción y cargados de forma inmediata.
España López, Antonio +6 more
core
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Advanced Science, EarlyView.Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
wiley +1 more source
Técnicas de exodoncia atraumática para la colocación de implantes inmediatos postextracción [PDF]
, 2017 Universidad de Sevilla.
Rivera Jiménez, Cristóbal Miguel
core
Evaluation of biofilm colonization on multi-part dental implants in a rat model [PDF]
, 2021 Eva Blank +7 more
openalex +1 more source
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Revista Médica Electrónica, 2014 La presencia de pacientes que acuden para su rehabilitación protésica mediante implantes osteointegrados en el maxilar posterior con dificultades es frecuente, debido a una disponibilidad ósea vertical insuficiente causada por la presencia del seno ...
Félix M Blanco Mederos +1 more
doaj
[Prevention of complications and risk reduction in oral implantology considering human factors and situation awareness]. [PDF]
Rev Cient Odontol (Lima), 2021 González-Silva NY +5 more
europepmc +1 more source