Results 91 to 100 of about 199,502 (291)

Evaluating the role of nanoparticles in enhancing bone regeneration in dental implantology

Journal of Pharmacy and Bioallied Sciences
Background: Dental implantology has witnessed substantial progress in recent years, driven by a growing emphasis on optimizing bone regeneration around dental implants.
K Sitamahalakshmi, Abhishek, P George Skariah, Reghunathan S Preethanath, Samiksha Dubey, Tazeen Dawood   +5 more
doaj   +1 more source

Comparative evaluation of osseointegration of new percutaneous implants made of Ti Grade 4 ultrafine‑grained alloy

Гений oртопедии, 2023
Introduction It has been shown that titanium implants with a structured surface provide an increased rate of osseointegration what makes their application quite promising.
Maksim V. Stogov, Andrey A. Emanov, Viktor P. Kuznetsov, Elena N. Gorbach, Elena A. Kireeva, Andrey V. Korelin   +5 more
doaj   +1 more source

Selective laser sintering of hydroxyapatite reinforced polyethylene composites for bioactive implants and tissue scaffold development [PDF]

, 2006
Selective laser sintering (SLS) has been investigated for the production of bioactive implants and tissue scaffolds using composites of high-density polyethylene (HDPE) reinforced with hydroxyapatite (HA) with the aim of achieving the rapid manufacturing
Berry E., Bonfield W., Boyan B. D., Chua C. K., Das S., Di Silvio L., Eniwumide J. O., Hing K. A., Kasemo B., Mercuri L. G., Mikos A. G., Rimell J. T., Tan K. H., Tanner K. E., Vacanti J. P., Vail N. K., Wang M., Williams J. D., Williams J. M., Zhang Y.   +19 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Biomimetic microelectronics for regenerative neuronal cuff implants [PDF]

, 2015
Smart biomimetics, a unique class of devices combining the mechanical adaptivity of soft actuators with the imperceptibility of microelectronics, is introduced.
Baunack, Stefan, Karnaushenko, Daniil, Karnaushenko, Dmitriy D, Koch, Britta, Makarov, Denys, Meyer, Anne K, Münzenrieder, Niko, Petti, Luisa, Schmidt, Oliver G, Tröster, Gerhard   +9 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

THE STUDY OF LOW-INTENSITY PULSED ULTRASOUND INFLUENCE ON WETTABILITY OF TITANIUM DENTAL IMPLANTS’ SURFACE IN EXPERIMENTAL MODEL

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The results of experimental studies, the purpose of which was to study the effect of low-intensity pulsed ultrasound on the wettability of the surface of titanium dental implants are described. We studied 64 titanium dental implants.
S. P. Rubnikovich, I. S. Khomich, V. T. Minchenya   +2 more
doaj  

Effect of zafirlukast on capsular contracture around silicone implants in rats Efeito do zafirlukast na contratura capsular ao redor de implantes de silicone em ratos

Acta Cirúrgica Brasileira, 2012
PURPOSE: To evaluate the effect of zafirlukast on capsular contracture around silicone implants by measuring the pressure within the implant, using a rat experimental model. METHODS: Forty adult female Wistar rats were used.
Érika Malheiros Bastos, Miguel Sabino Neto, Élvio Bueno Garcia, Daniela Francescato Veiga, Yuri Anna Han, Rafael Denadai, Rafael de Almeida Santos, Lydia Masako Ferreira   +7 more
doaj   +1 more source

Influence of the Compaction Pressure and Sintering Temperature on the Mechanical Properties of Porous Titanium for Biomedical Applications [PDF]

, 2019
In the present work, the use of porous titanium is proposed as a solution to the difference in stiffness between the implant and bone tissue, avoiding the bone resorption.
Castillo, Sandra M., Díaz, Eduardo, Muñoz Moreno, Sergio, Torres Hernández, Yadir, Trueba Muñoz, Paloma   +4 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source