Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Hybrid Versus Moderate Rough Implants in Periodontally Compromised Patients: A Randomized Controlled Split-Mouth Study. [PDF]
Dank A +5 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Delayed progressive fibrotic lung disease associated with bilateral silicone breast implant rupture: A case report. [PDF]
Bani Salem M +5 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
In vitro evaluation of torsional strength of orthodontic mini-implants
e aim of this study was to assess the maximum torsional strength of orthodontic mini-implants of different diameters. Methods: Eighteen mini-implants measuring 10 mm in length were divided into three groups (n = 6). G1, G2 and G3 had miniimplants of 1.2,
Matheus Melo Pithon, Rogério Lacerda dos Santos, Carla DAgostini Derech, Carlos Nelson Elias, Antônio Carlos de Oliveira Ruellas, Lincoln Issamu Nojima
core
Accuracy of CBCT and dental-MRI for detecting peri-implant bone defects at single titanium implants: an in-vitro pilot study. [PDF]
Hartung K +14 more
europepmc +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
3D Printing With Low-Cost and Recycled Medical-Grade Plastics: A Narrative Review of a Sustainable Pathway for Neurosurgical Tools, Training Models, and Implants in Low- and Middle-Income Countries. [PDF]
Najeeb ZU +9 more
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source

