Results 61 to 70 of about 407,817 (263)

Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis

Journal of Translational Medicine, 2022
Background The COVID-19 pandemic has become a huge threat to human health, infecting millions of people worldwide and causing enormous economic losses.
Keyu Kong, Yongyun Chang, Hua Qiao, Chen Zhao, Xuzhuo Chen, Kewei Rong, Pu Zhang, Minghao Jin, Jingwei Zhang, Huiwu Li, Zanjing Zhai   +10 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Implantoplasty and the risk of fracture of narrow implants with advanced bone loss: A laboratory study

, 2023
Objectives: To assess the impact of implantoplasty (IP) on maximum implant failure strength of narrow diameter implants of different type/design and material, with simulated advanced bone loss. Materials and Methods: Narrow, parallel-walled implants (3.3
Stavropoulos, Andreas, Flemming Isidor, Stavropoulos, Andreas,, Isidor, Flemming,, Per Vult von Steyern, Andreas Stavropoulos, Isidor, Flemming, Vult von Steyern, Per, Bertl, Kristina,, Bertl, Kristina, Kristina Bertl, Vult von Steyern, Per,   +11 more
core   +1 more source

Use of a Gigli Saw as a Substitute Osteotomy Tool When Oscillating Saw Malfunctions Occur During Hip Arthroplasty

Orthopaedic Surgery, 2022
Objective The oscillating saw has some inherent disadvantages, such as notch formation and blood splash. The objective is to introduce the Gigli saw as a substitute osteotomy tool when oscillating saw malfunctions occur during surgery. Methods During our
Keyu Kong, Yongyun Chang, Degang Yu, Yuanqing Mao, Yiming Zeng, Mengning Yan, Zanjing Zhai, Huiwu Li   +7 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Influência dos fatores locais e sistêmicos na osseointegração e perda óssea ao redor de implantes: estudo retrospectivo de 1 a 8 anos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-graduação em Odontologia, Florianópolis, 2010A proposta deste estudo foi avaliar, retrospectivamente, o sucesso dos implantes e a influência de ...
Souza, João Gustavo Oliveira de
core  

Prevalence of subjects with progressive bone loss at implants

, 2005
AIM: The aim of the present study was to assess the prevalence of subjects with progressive bone loss at implants with a function time of at least 5 years. MATERIAL AND METHODS: Radiographs of 1346 patients who had attended annual follow-up visits at the
Lekholm, Ulf,, Jemt, Torsten,, Fransson, Christer,, Berglundh, Tord,   +3 more
core   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science
Fatty acid synthase (FASN) is a central regulator of obesity through de novo lipogenesis (DNL), undergoes precise control via the ubiquitin‐proteasome system, yet its obesity‐related post‐translational modifications remain unclear.
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Electronic Properties of TiO2 Nanoparticles Films and the Effect on Apatite-Forming Ability

International Journal of Dentistry, 2013
Nanoparticle-covered electrodes have altered properties as compared to conventional electrodes with same chemical composition. The changes originate from the large surface area and enhanced conduction.
Johanna Löberg, Jenny Perez Holmberg, Ingela Mattisson, Anna Arvidsson, Elisabet Ahlberg   +4 more
doaj   +1 more source