Results 141 to 150 of about 7,741,883 (356)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

5-year trends in the intention to quit smoking amidst the economic crisis and after recently implemented tobacco control measures in Greece [PDF]

, 2014
Sotiria Schoretsaniti, Filippos T Filippidis, Constantine Vardavas, Christine Dimitrakaki, Panagiotis Behrakis, Gregory N. Connolly, Yannis Tountas   +6 more
openalex   +1 more source

Could the Implementation of Augmented Reality Influence Consumers’ Purchase Intention in E-Commerce? [PDF]

, 2023
Iisnawati Iisnawati, Taufiq Marwa, Muchsin Saggaff Shihab, Yuliani Yuliani, Dessy Yunita, Islahuddin Daud   +5 more
openalex   +1 more source

Implementation of ICT Policy (Blended Learning Approach): Investigating factors of Behavioural Intention and Use Behaviour

International Journal of Instruction, 2019
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Mohd Azli Yeop, M. Yaakob, Kung-Teck Wong, Y. Don, F. M. Zain   +4 more
semanticscholar   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Combining Self-Affirmation and Implementation Intentions: Evidence of Detrimental Effects on Behavioral Outcomes [PDF]

Background There is limited evidence that self-affirmation manipulations can promote health behavior change. Purpose The purpose of this study was to explore whether the efficacy of a self-affirmation manipulation at promoting exercise could be ...
Buckland, Nicola, Churchill, Susan, Harris, Peter, Jessop, Donna, Sparks, Paul   +4 more
core  

Sikap Konsumen Terhadap Produk Bundling Agribisnis [PDF]

, 2015
The objectives of the study are how to determine product bundling strategy and implementation to Dekalb brand hybrid corn and Round-up brand herbicide. By analyzes how consumer attitudes toward buying intention in this regard farmers as buyer
, Dr. Anton Agus Setyawan, M.Si, , Soepatini, Ph.D, Junaedi, Didi   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Bridging the gap between intentions and behavior: Implementation intentions, action control, and procrastination. [PDF]

, 2004
In the context of Ajzen’s (1991) theory of planned behavior, the antecedents of intentions are better understood than the antecedents of behavior. The current study aimed to improve the understanding of the transition from intentions to behavior.
Blonk, R.W.B. (Roland), Born, M.Ph. (Marise), Flier, H. (Henk) van der, Hooft, E.A.J. (Edwin) van, Taris, T.W. (Toon)   +4 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source