Results 141 to 150 of about 148,381 (298)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Exploring Mechanisms in Entrepreneurial Intention and Digital Entrepreneurial Behavior: The Moderating Effect of Psychological Resilience and Digital Literacy

open access: yesSAGE Open
The development of the digital economy has provided new opportunities for farmers in counties removed from the poverty list who want to start businesses to carry out digital entrepreneurship. Identifying how to effectively improve the transformation from
Feiyan Han, Herui Wang, Shuang Wu
doaj   +1 more source

Implementation Intentions [PDF]

open access: yes, 2019
Peter M. Gollwitzer, Gabriele Oettingen
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

PENGARUH PENDEKATAN IMPLEMENTATION INTENTION DALAM PENERAPAN MANAJEMEN PERAWATAN DIRI PADA PASIEN DIABETES MELLITUS TIPE 2 [PDF]

open access: yes, 2017
Sari, Dewi P. Pengaruh pendekatan implementation intention dalam penerapan manajemen perawatan diri pada pasien Diabetes Mellitus tipe 2, Fakultas Keperawatan, Universitas Airlangga Surabaya. Tesis.
Dewi Purnama Sari, 131514153042
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Participation in adult education: attitude and barriers. [PDF]

open access: yes, 2011
In this paper, we control the intention theory of Fishbein and Ajzen (1980) for the participation in an adult education course. Based on the Flemish Eurostat Adult Education Survey, we reveal that participants in adult education have a more positive ...
Boeren, Ellen
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Combating Fake News Using Implementation Intentions

open access: yesInformation Systems Frontiers
Abstract The rise of misinformation on social media platforms is an extremely worrisome issue and calls for the development of interventions and strategies to combat fake news. This research investigates one potential mechanism that can help mitigate fake news: prompting users to form implementation intentions along with education.
Inaiya Armeen   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy