Results 91 to 100 of about 58,349 (281)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Do implementation intentions help to turn good intentions into higher fruit intakes?

, 2006
OBJECTIVE: The present study examined (1) whether respondents who were encouraged to make implementation intentions to eat more fruit increased their fruit intakes, as measured by three measures of fruit intake; (2) whether the effects of implementation ...
Brug, J., de Vet, E.W.M.L., de Vries, N.K.; id_orcid, Vries, Nanne K., de, de Nooijer, J, de Vet, EWML, de Vries, NK, de Nooijer, J.; id_orcid, de Vries, N.K., Nooijer, Jascha, de, De Nooijer, J., Brug, Johannes, Brug, J, Vet, E.W.M.L. de, Vet, Emely, de, Vries, N.K. de, de Vet, E.   +16 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Water Intake - Implementation Intentions

This study aims to assess the effectiveness of implementation intentions as a means of increasing people's water ...
Esther K. Papies, Amy Rodger
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

38th Australian Psychological Society Annual Conference 2003

, 2003
This study determined the utility of measures of behavioural regulation in predicting spontaneous exercise implementation intentions. It was predicted that people who were intrinsically motivated to exercise would spontaneously set implementation ...
Brickell, Tracey A., Chatzisarantis, Nikos L. D., Pretty, Grace   +2 more
core  

Implementation Intentions and Disengagement from a Failing Course of Action

, 2006
We explored the consequences of forming implementation intentions that call for action (adjustment of chosen course of action) versus reflection (assessment of the appropriateness of chosen course of action) in situations that activate people s tendency ...
Gabriele Oettingen, Oettingen, Gabriele, Henderson, Marlone D., Marlone D. Henderson, Peter M. Gollwitzer, Gollwitzer, Peter M.   +5 more
core   +1 more source

Evidence that implementation intentions reduce self-harm in the community. [PDF]

Br J Health Psychol, 2023
Paterson A, Elliott MA, Nicholls LAB, Rasmussen S.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Can't do it, won't do it! Developing a theoretically framed intervention to encourage better decontamination practice in Scottish dental practices [PDF]

, 2009
Background: Guidance on the cleaning of dental instruments in primary care has recently been published. The aims of this study are to determine if the publication of the guidance document was enough to influence decontamination best practice and to ...
Ramsay, Craig R, Cassie, Heather, Clarkson Jan, Ramsay, Craig R., Irene Black, Jan Clarkson, Young, Linda, Clarkson, Jan; id_orcid, Bonetti, Debbie, Craig R Ramsay, Cassie, Heather; id_orcid, Debbie Bonetti, Heather Cassie, Linda Young, Black Irene, Black, Irene, Bonetti Debbie, Young Linda, Cassie Heather, Clarkson, Jan, Ramsay Craig R   +20 more
core   +1 more source