Results 161 to 170 of about 4,836,532 (286)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Implementation Leadership in Evidence-Based Practice in Healthcare: A Systematic Review and Meta-Analysis. [PDF]

Worldviews Evid Based Nurs
Kuha S, Miettunen J, Kanste O.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Enhancing Nurse Leaders Evidence-Based Practice Implementation Leadership Competence. A Systematic Review and Meta-Analysis of Educational Interventions. [PDF]

Worldviews Evid Based Nurs
Varpula J, Askola R, Kahsay DT, Axelin A, Virtanen L, Maijala R, Peltonen LM.   +6 more
europepmc   +1 more source

Evaluation of iLead, a generic implementation leadership intervention: mixed-method preintervention-postintervention design. [PDF]

BMJ Open, 2020
Richter A, Lornudd C, von Thiele Schwarz U, Lundmark R, Mosson R, Eskner Skoger U, Hirvikoski T, Hasson H.   +7 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Using the Implementation Leadership Scale (ILS) for nutrition incentive programs in the food retail context. [PDF]

Int J Behav Nutr Phys Act
Marriott JP, Byker Shanks C, Calloway EE, Yaroch AL, Prickitt J, Melendrez B, Knauer N, Houghtaling B.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

How Formal and Informal Nurse Leaders Enact Shared Implementation Leadership in a Hospital Setting. [PDF]

J Adv Nurs
Castiglione SA, Lavoie-Tremblay M, Kilpatrick K, Gifford W, Semenic SE.   +4 more
europepmc   +1 more source