Results 161 to 170 of about 7,716,939 (299)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Implementation of Workshop outcomes

Implementation of workshop outcomes to feed back into iterative cycle of improvement ready for WP6 full ...
openaire   +1 more source

Effectiveness, safety, and implementation outcomes of a decentralization program to deliver antivenoms in the Western Brazilian Amazonia: The SAVING program. [PDF]

PLoS Negl Trop Dis
Monteiro W, Murta F, Serrão-Pinto T, Machado V, de Farias AS, Dos Santos AC, Cardoso D, Guimarães Figueira EA, da Silva Chagas ÉC, Habibe LS, da Silva Ipuchima L, de Souza NF, da Silva Lima T, Dourado FS, Montebello L, de Lima-Junior FEF, Casewell NR, Lalloo DG, Almeida-Val F, Lacerda M, Vissoci JRN, Gerardo CJ, Wen FH, Sachett J.   +23 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Implementation Outcomes and Impact of a School Health and Wellness Network Specialist Intervention in Chicago Public Schools. [PDF]

J Public Health Manag Pract
Chriqui JF, Leider J, Jarpe-Ratner E, Offstein M, Lin YC, Zolfo S, Simon J, Tully J, DeClemente T.   +8 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Partially-honest Nash implementation: Characterization results [PDF]

This paper studies implementation problems in the wake of a recent trend of implementation of non-consequentialist nature, which draws on the evidence taken from experimental and behavioral economics.
Yoshihara, Naoki, Lombardi, Michele
core  

Implementation outcomes of AI documentation support in routine clinical practice: A non-randomized controlled trial. [PDF]

PLOS Digit Health
Heilmeyer FA, Lyssenko L, Reinhard T, Haverkamp C, Böhringer D.   +4 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source