Results 141 to 150 of about 4,099,697 (298)

Integrating training in evidence-based medicine and shared decision-making: a qualitative study of junior doctors and consultants

BMC Medical Education
Background In the past, evidence-based medicine (EBM) and shared decision-making (SDM) have been taught separately in health sciences and medical education.
Mary Simons, Georgia Fisher, Samantha Spanos, Yvonne Zurynski, Andrew Davidson, Marcus Stoodley, Frances Rapport, Louise A. Ellis   +7 more
doaj   +1 more source

Orchestration of the Marketing Strategy under Competitive Dynamics [PDF]

Constructing suitable marketing strategy and implementing it effectively is an art and science both like orchestration of a symphony. The discussion in this paper blends this analogy with the science of marketing demonstrating the levels of strategy ...
Rajagopal
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

SCIENCE TEACHING IMPROVEMENT IN JAPAN: THE THREE STEPS OF CONSTRUCTIVIST LEARNING [PDF]

Constructivist learning (CL), although the basic principles of the theory have been developed for years, has recently become a prominent approach in teaching and learning science. The implementation of the theory in schools, however, is still problematic:
Slamet , Suyanto, Yoshisuke, Kumano
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Patient and provider perspectives on implementing patient navigation for colorectal cancer screening for Black and Latine patients: a qualitative study

BMC Health Services Research
Background In the United States, Black people experience inequities in colorectal cancer (CRC) screening access, contributing to CRC outcome inequities. Latine people in the US and have lower screening rates (53.4% vs. 70.4% for White people), and CRC is
Katarina E. AuBuchon, Laura C. Schubel, Jessica N. Rivera Rivera, Demetrie Garner, Jennifer Tran, Sophia Urdinola, Hannah Arem   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Benefits, implementation and sustainability of innovative paediatric models of care for children with type 1 diabetes: a systematic review

BMC Pediatrics
Background and aim The evidence about the acceptability and effectiveness of innovative paediatric models of care for Type 1 diabetes is limited. To address this gap, we synthesised literature on implemented models of care, model components, outcomes ...
Ann Carrigan, Isabelle Meulenbroeks, Mitchell Sarkies, Genevieve Dammery, Nicole Halim, Nehal Singh, Rebecca Lake, Elizabeth Davis, Timothy W. Jones, Jeffrey Braithwaite, Yvonne Zurynski   +10 more
doaj   +1 more source

UV-optical from space [PDF]

The following subject areas are covered: (1) the science program (star formation and origins of planetary systems; structure and evolution of the interstellar medium; stellar population; the galactic and extragalactic distance scale; nature of galaxy ...
Angel, J. Roger, Blandford, Roger D., Boggess, Albert, Bowyer, C. Stuart, Carruthers, George R., Cowie, Lennox L., Doschek, George A., Dupree, Andrea K., Illingworth, Garth, Savage, Blair   +9 more
core   +1 more source