Results 131 to 140 of about 1,049,300 (304)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A methodology for effective implementation of lean strategies and its performance evaluation in manufacturing organizations

, 2013
Purpose – \ud The purpose of this paper is to develop an effective methodology for implementing lean manufacturing strategies and a leanness evaluation metric using continuous performance measurement (CPM).\ud \ud Design/methodology/approach – \ud Based ...
Karim, Azharul, Arif-Uz-Zaman, Kazi
core   +1 more source

IMPACT-FH Study for Implementing Innovative Family Communication and Cascade Testing Strategies for Familial Hypercholesterolemia

JACC: Advances
Background: Relatives of probands diagnosed with familial hypercholesterolemia (FH) should undergo cascade testing for FH. Objectives: The purpose of this study was to evaluate probands’ choices of innovative strategies to communicate their FH result ...
Laney K. Jones, PharmD, MPH, Gemme Campbell-Salome, PhD, Nicole L. Walters, BS, Andrew Brangan, BS, Kelly M. Morgan, MS, Eric P. Tricou, MS, Zoe T. Lindsey Mills, BS, Mary P. McGowan, MD, Samuel S. Gidding, MD, Alicia M. Johns, PhD, H. Lester Kirchner, PhD, Alanna Kulchak Rahm, PhD, Amy C. Sturm, MS   +12 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Theory of Implementation of Social Choice Rules [PDF]

Suppose that the goals of a society can be summarized in a social choice rule, i.e., a mapping from relevant underlying parameters to final outcomes.
Roberto Serrano
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Differences in implementation strategies of the European Resuscitation Council Guidelines 2015 in Danish hospitals – a nationwide study

, 2018
Mathilde Stærk,1–3 Kasper G Lauridsen,1–3 Troels Mygind-Klausen,1–3 Bo Løfgren2–5 1Clinical Research Unit, Randers Regional Hospital, Randers, Denmark; 2Research Center for Emergency Medicine, Aarhus University ...
Lauridsen KG, Mygind-Klausen T, Løfgren B, Stærk M   +3 more
core  

Editorial: Understanding, assessing, and guiding adaptations in public health and health systems interventions: current and future directions

Frontiers in Public Health, 2023
Roman Aydiko Ayele, Roman Aydiko Ayele, Borsika Adrienn Rabin, Borsika Adrienn Rabin, Borsika Adrienn Rabin, Borsika Adrienn Rabin, Marina McCreight, Marina McCreight, Catherine Battaglia, Catherine Battaglia   +9 more
doaj   +1 more source