Results 101 to 110 of about 765,826 (273)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

HOW RURAL INSTRUCTOR IMPLEMENTS ENGLISH FOR SPECIFIC PURPOSES (ESP): INSTRUCTOR’S PERCEPTION [PDF]

open access: yesCeltic, 2020
Teaching ESP is necessary to be designed by the ESP instructors because one of the teaching ESP requirements is the instructors must prepare the suitable precision of English materials for the ESP students. Hyland (2008:113) states that “designing lesson
Yani Faturrachman, Dady Sulaiman
doaj  

MatchIt: Nonparametric Preprocessing for Parametric Causal Inference [PDF]

open access: yes
MatchIt implements the suggestions of Ho, Imai, King, and Stuart (2007) for improving parametric statistical models by preprocessing data with nonparametric matching methods.
Daniel Ho   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Binscatter Regressions

open access: yes, 2019
We introduce the \texttt{Stata} (and \texttt{R}) package \textsf{Binsreg}, which implements the binscatter methods developed in \citet*{Cattaneo-Crump-Farrell-Feng_2019_Binscatter}. The package includes the commands \texttt{binsreg}, \texttt{binsregtest},
Cattaneo, Matias D.   +3 more
core  

Glider: A GPU Library Driver for Improved System Security [PDF]

open access: yes, 2014
Legacy device drivers implement both device resource management and isolation. This results in a large code base with a wide high-level interface making the driver vulnerable to security attacks.
Sani, Ardalan Amiri   +2 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Short History of Grinding Implements for Domestic Use in Japan

open access: yesKONA Powder and Particle Journal, 2014
There are many works that refer to the history of grinding implements1~6), but they are restricted mainly to the origin of Western wheat flour milling technology as a professional activity, and do not always pay attention to domestic use.
Shigeo Miwa   +2 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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