Results 101 to 110 of about 740,358 (338)

Mapping Charge Interactions in Intrinsically Disordered Proteins

open access: yesAdvanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips   +14 more
wiley   +1 more source

An Approach to Incorporating Implicit Knowledge in Object Detection Models

open access: yesApplied Sciences
Current object detection methods typically focus on addressing the distribution discrepancies between source and target domains. However, solely concentrating on this aspect may lead to overlooking the inherent limitations of the samples themselves. This
Wenbo Peng, Jinjie Huang
doaj   +1 more source

Finite-strain formulation and FE implementation of a constitutive model for powder compaction

open access: yes, 2014
A finite-strain formulation is developed, implemented and tested for a constitutive model capable of describing the transition from granular to fully dense state during cold forming of ceramic powder.
Bigoni, D.   +2 more
core   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

open access: yesAdvanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu   +13 more
wiley   +1 more source

Evidence for a competitive relationship between executive functions and statistical learning

open access: yesnpj Science of Learning
The ability of the brain to extract patterns from the environment and predict future events, known as statistical learning, has been proposed to interact in a competitive manner with prefrontal lobe-related networks and their characteristic cognitive or ...
Felipe Pedraza   +10 more
doaj   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

open access: yesAdvanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Adaptively Implicit Advection for Atmospheric Flows

open access: yesJournal of Advances in Modeling Earth Systems
Implicit time‐stepping for advection is applied locally in space and time where Courant numbers are large, but standard explicit time‐stepping is used for the remaining solution which is typically the majority.
Hilary Weller   +2 more
doaj   +1 more source

Atomistic Insights into the Electrochemical Oxygen Evolution Activity of Hollandite IrO2 Surfaces

open access: yesAdvanced Science, EarlyView.
Lattice distortions at tunnel‐structured hollandite IrO2 surfaces reshape Ir‐O bonding: they weaken the σ‐bond contribution in the Ir‐*OH bond while enhancing the π contribution of the Ir‐*O bond. This orbital reorganization in hollandite surfaces stabilizes *O, facilitates the *OH → O step, and lowers the oxygen‐evolution reaction overpotential ...
Sangseob Lee   +3 more
wiley   +1 more source

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