A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Transformer and graph variational autoencoder to identify microenvironments: A deep learning protocol for spatial transcriptomics. [PDF]
Paniagua K +5 more
europepmc +1 more source
The IQ-compete assay for measuring mitochondrial protein import efficiencies in living yeast cells. [PDF]
Hoffman Y +3 more
europepmc +1 more source
Evolution of Plant AIG1-like Proteins: Different Modes of Sequence Divergence and Their Contributions to Functional Diversification. [PDF]
Peng J, Xia L, Wang J, Guo C.
europepmc +1 more source
Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]
Nath BK +7 more
europepmc +1 more source
Ran modulates allosteric crosstalk between importin β surfaces. [PDF]
Ko YH +6 more
europepmc +1 more source
Linking RayStation AI auto-contouring with Eclipse TPS: a scripted workflow for clinical integration. [PDF]
Ryczkowski A, Jodda A, Piotrowski T.
europepmc +1 more source
Intercellular mitochondrial transfer and transmitophagy in response to protein import dysfunction
Glover E +5 more
europepmc +1 more source

