Results 331 to 340 of about 1,757,599 (384)

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao   +8 more
wiley   +1 more source

A Nanostructured Ru‐Mn‐Nb Alloy with Oxygen‐Enriched Boundaries for Ampere‐Level Hydrogen Evolution

open access: yesAdvanced Science, EarlyView.
Ru62Mn12Nb21O5 medium‐entropy alloy with a crystal‐crystal dual‐phase structure is deposited on a carbon cloth substrate by the magnetron sputtering method. The oxygen‐rich interface induced by the rich Mn phase and the poor Mn phase optimized the electronic structure of the catalyst, adjusted the adsorption and desorption processes of intermediates ...
Jie Li   +12 more
wiley   +1 more source

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration. [PDF]

open access: yesmBio
Ingram Z   +12 more
europepmc   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

National consumption of antimicrobials intended for use in animal livestock health: a retrospective data analysis of antimicrobial imports to Uganda from 2018 to 2020. [PDF]

open access: yesBMC Vet Res
Kitutu FE   +10 more
europepmc   +1 more source

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