Results 81 to 90 of about 25,085 (250)

Reasoned opinion on the modification of the existing MRL for thiram in avocados [PDF]

EFSA Journal, 2015
In accordance with Article 6 of Regulation (EC) No 396/2005, Belgium, hereafter referred to as the evaluating Member State (EMS), received an application from Taminco N.V.
European Food Safety Authority
doaj   +1 more source

Cytochrome P450 Inhibitors Reduce Creeping Bentgrass (Agrostis stolonifera) Tolerance to Topramezone. [PDF]

, 2015
Creeping bentgrass (Agrostis stolonifera L.) is moderately tolerant to the p-hydroxyphenylpyruvate dioxygenase-inhibiting herbicide topramezone. However, the contribution of plant metabolism of topramezone to this tolerance is unknown.
Mueller, Thomas C., Matthew T Elmore, Elmore, Matthew T., Armel, Gregory R., Sorochan, John C., Best, Michael D., Dean A Kopsell, Michael D Best, Kopsell, Dean A., James T Brosnan, John C Sorochan, Thomas C Mueller, Gregory R Armel, Riechers, Dean E., Brosnan, James T.   +14 more
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Reasoned opinion on the setting of an import tolerance for didecyldimethylammonium chloride (DDAC) in citrus [PDF]

EFSA Journal, 2013
In accordance with Article 6 of Regulation (EC) No 396/2005, The Netherlands, hereafter referred to as the evaluating Member State (EMS), received an application from Exponent International Ltd (on behalf of ICA International Chemicals (PTY) Ltd) to set ...
European Food Safety Authority
doaj   +1 more source

Functions of plastid protein import and the ubiquitin–proteasome system in plastid development

, 2015
Plastids, such as chloroplasts, are widely distributed endosymbiotic organelles in plants and algae. Apart from their well-known functions in photosynthesis, they have roles in processes as diverse as signal sensing, fruit ripening, and seed development.
Jarvis, Paul, Ling, Qihua
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

What is important in theorizing tolerance today? [PDF]

Contemporary Political Theory, 2015
if one wants to grasp tolerance politically, that is, as a problem of power and as organizing relations among citizens, subjects, peoples or states, then it must be understood, inter alia, as being enacted through contingent, historically specific discourses - linguistically organized norms operating as common sense.
Brown, Wendy, Dobbernack, Jan, Modood, Tariq, Newey, Glen, March, Andrew F., Tønder, Lars, Forst, Rainer   +6 more
openaire   +3 more sources

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Setting of import tolerances for metalaxyl‐M in oil palms fruits and peppercorn

, 2023
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Syngenta Crop Protection AG submitted a request to the competent national authority in Belgium to set an import tolerance for the active substance metalaxyl‐M in oil palms fruits ...
Renata Leuschner, Hermine Reich, Stefanie Nave, Ragnor Pedersen, Silvia Ruocco, Giulia Bellisai, Anne Theobald, Irene Castellan, Luna Greco, Miguel Santos, EFSA (European Food Safety Authority), Alessia Verani, Giovanni Bernasconi, Monica Del Aguila, Samira Jarrah, Ileana Miron, Luis Carrasco Cabrera, Alessia Pia Scarlato, Alba Brancato, Lucien Ferreira, Manuela Tiramani, German Giner Santonja   +21 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source