Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Sustainable Home Meal Replacement (HMR) Consumption in Korea: Exploring Service Strategies Using a Modified Importance-Performance Analysis. [PDF]
Foods, 2022 Ji Y, Han J.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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OTT Streaming Distribution Strategies for Dance Performances in the Post-COVID-19 Age: A Modified Importance-Performance Analysis. [PDF]
Int J Environ Res Public Health, 2021 Kim J, Kim E, Hong A.
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Importance-Performance Analysis (IPA) in Researching the Satisfaction of Simulation
International Journal of Gaming and Computer-Mediated SimulationsStudents are the customers of higher education, and their satisfaction directly influences service quality in the tertiary sector. It is essential, therefore, to research students' views. This can be done by applying important-performance analysis (IPA), an effective tool for achieving satisfaction.
Qi Lai, John Denholm
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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Importance-Performance Analysis of Health Perception among Korean Adolescents during the COVID-19 Pandemic. [PDF]
Int J Environ Res Public Health, 2021 Lee SM, So WY, Youn HS.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Application of Uninorms in Importance-Performance Analysis
, 2006 In the field of marketing, Importance-Performance Analysis is a useful technique for evaluating the elements of a marketing program. The importance dimension of this technique is often determined in a regression based approach. However, this approach has certain problems and limitations. A new approach, based on uninorms, is suggested.
Depaire, B., Vanhoof, K., Wets, G.
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