Results 51 to 60 of about 1,153,181 (253)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Analyzing Key Quality Attributes in Commercial Space Design Planning Using Impact Range Performance Analysis by Computer Software for Sustainable Development Goals

open access: yesEngineering Proceedings
For intensified global environmental and societal challenges, the Sustainable Development Goals (SDGs) have come to the forefront as a pivotal framework for corresponding action.
Chun-Pin Huang   +2 more
doaj   +1 more source

Tourists’ Satisfaction at Trijuginarayan: An Emerging Spiritual and Adventure Tourist Destination in Garhwal Himalaya India [PDF]

open access: yesTurizam, 2015
Tourists’ satisfaction has been acknowledged as one of the most important elements of competitive advantage and formulating effective destination management strategies because it is a reliable standard to evaluate performance of tangible and intangible ...
S.C. Bagri, Devkant Kala
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

EVALUATING HIGHER EDUCATION WEBSITE QUALITY USING WEBQUAL 4.0 AND IMPORTANCE PERFORMANCE ANALYSIS (IPA)

open access: yesPilar Nusa Mandiri
LLDikti Region III is a unit operating under the Ministry of Education, Culture, Research, and Technology, responsible for promoting the enhancement of higher education quality in Jakarta. One of the media used by LLDikti Region III to serve stakeholders
Wiji Murdoko, Ihsan Jatnika
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Pengukuran Kualitas Layanan di Universitas Kristen Indonesia (UKI)

open access: yesBinus Business Review, 2012
The purpose of this study was to determine the service quality that was held by UKI based on student’s perceptions. The method used in this study is the survey method on UKI’s students using questionnaires.
Freddy Simbolon
doaj   +1 more source

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