Results 201 to 210 of about 5,530,708 (310)

Embodiment, Relationships, and Sexuality: An Ethical Analysis of Extended Reality Technologies. [PDF]

open access: yesSci Eng Ethics
Ramirez EJ   +6 more
europepmc   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

open access: yesAdvanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu   +9 more
wiley   +1 more source

Dreams: The Mind's Minecraft. [PDF]

open access: yesCureus
Nashwan AJ, Hendy A, Abujaber AA.
europepmc   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

A Versatile Three Dimensional Traction Force Microscopy Framework for Uncovering the Mechanics of Bio‐Adhesion

open access: yesAdvanced Science, EarlyView.
This study introduces a versatile platform for quantifying three dimensional traction forces at bio‐adhesive interfaces. Integrating in situ stereo‐digital image correlation with finite element simulations allows for precise measurement of microscale displacements and traction forces in both dry and wet conditions.
Yingwei Hou, Fusheng Wang, Tao Liu
wiley   +1 more source

A Sustainable Adhesive Paradigm: Reversibly Reinforcing, Heat‐Free Bonding with Universal Substrates

open access: yesAdvanced Science, EarlyView.
A heat‐free adhesive system, delivering superior adhesion strength across metal, plastic, and glass substrates, is developed. Repeatable bonding with reinforcement instead of strength reduction enables error‐tolerant applications. This design paradigm establishes an eco‐friendly alternative to conventional adhesives, particularly suitable for ...
Shuang Zhang   +5 more
wiley   +1 more source

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