Results 81 to 90 of about 21,145 (299)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Theoretical approaches for understanding impoverishment and socio spatial segregation [PDF]

open access: yes, 2018
The purpose of this article is to provide a theoretical and methodological basis for the study and understanding of the processes of impoverishment and socio-spatial segregation that occur in our societies in contemporary contexts, where capitalist ...
Valderrama-Barrera, Martha   +8 more
core   +1 more source

Hydrological degradation of automorphic soils in agricultural landscapes

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2012
The impoverishment of physical and water properties resulted from the use in agriculture for a long period of time is exemplified by soddy-podzolic, gray soils and chernozems.
G. S. Bazykina
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Medicaid--transfers of assets and spousal impoverishment

open access: yes, 1995
"October 18, 1995."; Discusses Medicaid transfer of assets law, including a description of the "spousal impoverishment" provisions.; Harvested from the web on 8/21 ...
Cohen, Robin, 1959-
core  

Indian community health insurance schemes provide partial protection against catastrophic health expenditure. [PDF]

open access: yes, 2007
BACKGROUND: More than 72% of health expenditure in India is financed by individual households at the time of illness through out-of-pocket payments. This is a highly regressive way of financing health care and sometimes leads to impoverishment.
Ranson, Kent   +19 more
core   +2 more sources

Impoverishment after caesarean section and the impact of the free health care initiative.

open access: yes, 2021
Impoverishment after caesarean section and the impact of the free health care initiative.
Lars Hagander (3170169)   +9 more
core   +1 more source

How does digital literacy reduce the risk of re-impoverishment of low-income rural households: an empirical study based on CFPS data from 2016 to 2022

open access: yesFrontiers in Sustainable Food Systems
ObjectiveEffectively preventing rural low-income households from returning to poverty is a core strategic requirement for improving China’s normalized poverty support system.
Zongfei Liu
doaj   +1 more source

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