Results 91 to 100 of about 253,842 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Dentists’ Knowledge about Different Impression Techniques for Making Removable Prosthodontics in Isfahan [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2004
Introduction. One of the most important procedures in making removable prosthodontics, is impression making. This study tried to assess the knowledge of dentists in Isfahan city about different impression techniques for making removable prosthodontics ...
Ramin Moshref, Nina Sadrieh
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Negative Deviation Effect in Interpersonal Communication: Why People Underestimate the Positivity of Impression They Left on Others

open access: yesPsychology Research and Behavior Management, 2020
Jiamin Li,1,2 Zhenchao Zhong,1,2 Lei Mo1,2 1Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, Guangzhou 510631, People’s Republic of China; 2School of Psychology, Center for Studies of Psychological Application ...
Li J, Zhong Z, Mo L
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

POSSIBILITIES AND LIMITATIONS OF DIGITAL IMPRESSIONS IN COMPLETE REMOVABLE DENTURE PROSTHETICS

open access: yesУкраїнський стоматологічний альманах
Relevance. The fabrication of complete dentures for edentulous jaws is a cornerstone of prosthetic dentistry, and retention is a critical factor for clinical success.
O.V. Shemetov
doaj   +1 more source

Narrating the Impression

open access: yes, 2019
The aim of this contribution is to expand the notion of ecosystems deterioration beyond its necessary but limited materialist sense to include the flattening of their perceptive qualities. Defining the ecosystem as a set of complex relationships between the living subjects and the environment, this essay argues that such relationships include ...
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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