Results 201 to 210 of about 253,842 (268)

Accuracy of 3 Intraoral and 1 Extraoral Digital Scanning Systems for Multiple Laminate Veneer Preparations: An In Vitro Study. [PDF]

Med Sci Monit
Ahmad M, Sayed ME, Abdul HN, Basihi MA, Khalawi AM, Jokhadar HF, Muaddi MH, AlResayes SS, Alqarawi FK, Althubaitiy RO, Alshammakhy R, Alsaeed AY, Zidane B.   +12 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Integration of Digital Denture Technology in the Prosthodontic Management of Pediatric Osteopetrosis: A Case Report. [PDF]

Case Rep Dent
Niakou A, Kamalakidis S, Stratos A, Arapostathis K, Kotsiomiti E.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Clinically Meaningful Score Difference and Meaningful Score Regions in Positive and Negative Syndrome Scale Total Score from Post Hoc Analyses of a Phase 3 Pivotal Clinical Trial of Transdermal Asenapine in Patients with Schizophrenia. [PDF]

Neuropsychiatr Dis Treat
Citrome L, Czobor P, Komaroff M, Khan M, Hasebe M, Terahara T.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Survey on Dental Students' Knowledge of Infection Prevention and Control Rules. [PDF]

Dent J (Basel)
Stoeva V, Miteva-Katrandzhieva T, Shamsee E.   +2 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Marginal Fit Evaluation of Zirconia Copings Based on Conventional and Digital Impressions Using a Tooth Section Microscopic Examination Technique. [PDF]

Dent J (Basel)
Schulze M, Ottl P, Warkentin M.
europepmc   +1 more source

Reliability and Practicability of FAP-RADS Version 1.0 for Structured Reporting of FAPI Imaging in Pulmonary and Urothelial Carcinoma. [PDF]

J Nucl Med
Novruzov E, Mamlins E, Widjaja L, Siegmund SC, Watabe T, Mori Y, Stief C, Tufman A, Herrmann K, Gorin MA, Pomper MG, Rowe SP, Giesel FL, Werner RA, Sheikh GT.   +14 more
europepmc   +1 more source